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Downstream ultrafiltration/diafiltration concentration process: How to effectively prevent target protein permeation and loss In downstream purification processes for recombinant proteins, blood pr...

I. What Is Membrane Chromatography? Membrane chromatography uses porous separation membranes as the chromatographic medium, with specific ligands immobilized on the membrane surface. By relying on ...

Guidling Technology to Exhibit Biopharmaceutical Filtration & TFF Solutions at CPHI Milan 2026 Hangzhou Guidling Technology Co., Ltd. invites pharmaceutical professionals worldwide to visit Boo...

Membrane chromatography is a technology used for the separation and purification of proteins and biomolecules during downstream processing. It is considered an effective alternative to conventional...

traditional packed-bed chromatography is mature and reliable, but it is constrained by limitations such as low diffusion efficiency, high backpressure, and slow processing speeds, making it increas...

Many people experience recurrent redness, stinging, and a feeling of irritation after using recombinant collagen products. The root cause is often not the collagen itself, but residual endotoxins (...

1. Installation Install the hollow fiber module and connect all tubing. Place the feed tubing into purified water, and place both the retentate tubing and permeate tubing into a waste container. 2....

What should be done if the design space established during process characterization is either broader or narrower than the operating parameter ranges used for manufacturing Phase III clinical trial...

We purchased membrane cassettes with the same MWCO from two different manufacturers. During diafiltration experiments, we observed a significant difference in product recovery. Further analysis sho...

Tangential Flow Filtration (TFF) is widely used in both biopharmaceutical and chemical pharmaceutical processing as a key technology for buffer exchange and purification. Among all process componen...

Solid-phase peptide synthesis (SPPS) is a method for synthesizing peptides on a solid support. The main SPPS strategies include the Boc method and the Fmoc method . Peptide synthesis is a repetitiv...

Peptide therapeutics, due to their strong targeting ability and high safety profile, have become key treatment options for diseases such as diabetes and cancer. However, the complex impurities gene...