Your Professional Hollow Fiber Supplier
Hangzhou Guidling Technology Co., Ltd. is an innovative manufacturer established in 2015, specializing in downstream biopharmaceutical purification and separation solutions. We focus on clarification, concentration, and filtration processes for biological production. Our main products include ultrafiltration & microfiltration cassettes, TFF systems, centrifugal filter devices, depth filter modules, and virus removal filters. These products are widely used in antibodies, vaccines, diagnostics, blood products, and cell culture applications.
Stable Manufacturing Capability
We have a complete production system for filtration products, ensuring consistent quality and stable supply. Our manufacturing process is designed to meet industrial biopharmaceutical standards.
Continuous Product Development
We keep improving our filtration technologies and have developed multiple product series since 2015. This allows us to provide updated and efficient solutions for downstream purification needs.
Flexible Application Solutions
Our products are designed for different bioprocess stages, including clarification, concentration, and virus removal. This helps customers build more efficient and customized filtration workflows.
Reliable Cooperation Support
We focus on long-term cooperation with customers by providing responsive communication and technical assistance. Our aim is to support smooth project operation from selection to application.
Parameter
|
Specs |
tube inner diameter（mm) |
Tube Outer diameter（mm) |
Valid length（cm) |
Inner diameter of fiber（mm) |
Processing capacity |
MWCO |
Fiber quantity |
Filter area |
Inlet/reflux |
Permeate |
|
xs |
13 |
16 |
30 |
1.0 |
<1L |
30kd 100kd 300kd 500kd 750kd 0.2um 0.45um |
10 |
94cm2 |
25TC |
Luer |
|
S |
13 |
16 |
30 |
1.0 |
<3L |
28 |
260cm² |
|||
|
M |
36 |
40 |
30 |
1.0 |
<15L |
160 |
0.15㎡ |
25TC/50TC |
25TC |
|
|
60 |
1.0 |
<30L |
160 |
0.3㎡ |
||||||
|
L |
108 |
114 |
60 |
1.0 |
<500L |
2400 |
4.5㎡ |
Not applicable |
Not applicable |
|
|
120 |
1.0 |
<1000L |
2400 |
9㎡ |
The hollow fibers produced by our company mainly include the following types:
Hollow Fiber Membrane
Hollow fiber membrane is an ultra-fine, straw-like tube that acts as a physical filter to separate particles and molecules from liquids or gases.
Hollow Fiber Filter
Hollow fiber filter is a highly efficient filtration device consisting of a bundle of thousands of tiny, straw-like semi-permeable tubes.
Advantages of Hollow Fiber
Increased Surface Area
The tubular structure of hollow fiber translates to a significantly increased surface area. This characteristic enhances the contact between the medium and the cells, leading to higher productivity and improved yields.
Enhanced Mass Transfer
Efficient mass transfer is a critical factor in biopharmaceutical production. Hollow fiber technology excels in this aspect, facilitating rapid exchange of nutrients and metabolites, ultimately maximizing the efficiency of the production process.
Cost-Effective Solutions
Beyond its technical advantages, hollow fiber technology offers cost-effective solutions for biopharmaceutical companies. The streamlined processes and increased productivity contribute to a more economically viable production model.
Applications of Hollow Fiber
Protein concentration and purification
One of the most common applications of hollow fiber filters is in protein concentration, purification, and diafiltration. Their high surface area and low protein-binding PES material make them ideal for handling delicate biological molecules.
Cell harvest and clarification
In bioprocessing, hollow fiber filters are widely used for clarifying cell cultures and recovering microbial or mammalian cells. The outside-in or inside-out filtration modes allow flexibility in processing fermentation broths, cell suspensions, or other complex mixtures.
Virus and vaccine processing
Another critical use of hollow fiber filters is in virus concentration and vaccine manufacturing. Hollow fibers can separate viruses, virus-like particles (VLPs), or extracellular vesicles (EVs) while maintaining structural integrity.
Nanomaterials and particle fractionation
Beyond life sciences, hollow fiber filters are used in processing nanomaterials and suspensions. They can fractionate particles by size, concentrate colloids, and purify nano-formulations.
Difference Between Microfiber and Hollow Fiber
|
Feature |
Microfiber |
Hollow Fiber |
|
Structure |
Solid fiber |
Tube-shaped fiber |
|
Surface Area |
Lower |
Very high |
|
Filtration Performance |
Moderate |
Excellent |
|
Pressure Resistance |
Good |
Depends on design |
|
Typical Use |
Textiles, surface cleaning |
Water treatment, bioprocessing, clarification |
Storage Precautions for Hollow Fibers
The new mbr membrane should be stored indoors and in a cool and dry place without direct sunlight. The indoor temperature range should be at -0°℃~45℃.
The MBR membrane stored in 1% SMBS standard protective solution will freeze below -4°c, so the temperature should not be too low.
If it is not used for the time being, we should keep the components in the original packaging as much as possible. Generally speaking, if the indoor temperature is not lower than 45 C, it is necessary to check the growth of microorganisms inside the membrane element every 3 months. If the protective solution is cloudy, remove the packaging bag, re-immerse the MBR membrane element in the protective solution, take out after 1 hour, drain it, and then re-seal it.
If there is no equipment for storage, the new hollow fiber MBR membrane element can be stored in the original protective liquid bag for up to 12 months. We should clean it before into used.
The pH value of the mbr hollow fiber membrane preservation solution should be greater than 3. The pH value will decrease when sodium hydrogen sulfite is oxidized to sulfuric acid.
Ordering Process
- Send us your order list (models/quantities)
- We will send you PROFORMA INVOICE (PI) with shipping cost and Payment information for your confirmation.
- You arrange payment after you confirmed proforma invoice, we will arrange production after received your payment notice.
- Specific delivery date depends on your specific needs, normally delivery in 1-3 days.
- We will arrange delivery after your payment arrived and goods ready, and at the same time we will tell you goods tracking number so that you could know your goods condition by this number from courier site.
- You will receive your order in about 3-5 days after goods ship out.
Packaging and Shipping
|
Packaging |
Inner Packaging: Sterile protective bag or shrink wrap Outer Packaging: Extra-thick cardboard carton |
|
Shipping |
For small quantity or sample will be shipped by DHL, FEDEX ,TNT ( shipping days 3-4 days). For bigger quantity will be shipped by sea shipment to your pointed nearest seaport ( shipping days 1 month). |
Our Factory
Our factory is located in the Hangzhou City, we have 5 production lines, which can produce 8000pcs cassettes and 5000pcs holders, and have about 100 workers in the factory.
We're well-known as one of the leading hollow fiber manufacturers and suppliers in China. If you're going to wholesale bulk high quality hollow fiber in stock, welcome to get free sample from our factory.
