Depth Filter

Your Professional Depth Filter Supplier

Hangzhou Guidling Technology Co., Ltd. is an innovative manufacturer established in 2015, specializing in downstream biopharmaceutical purification and separation solutions. We focus on clarification, concentration, and filtration processes for biological production. Our main products include ultrafiltration & microfiltration cassettes, TFF systems, centrifugal filter devices, depth filter modules, and virus removal filters. These products are widely used in antibodies, vaccines, diagnostics, blood products, and cell culture applications.

Stable Manufacturing Capability
We have a complete production system for filtration products, ensuring consistent quality and stable supply. Our manufacturing process is designed to meet industrial biopharmaceutical standards.

Continuous Product Development
We keep improving our filtration technologies and have developed multiple product series since 2015. This allows us to provide updated and efficient solutions for downstream purification needs.

Flexible Application Solutions
Our products are designed for different bioprocess stages, including clarification, concentration, and virus removal. This helps customers build more efficient and customized filtration workflows.

Reliable Cooperation Support
We focus on long-term cooperation with customers by providing responsive communication and technical assistance. Our aim is to support smooth project operation from selection to application.

Depth filters are commonly used when the fluid to be filtered contains a high dirt load or where extended filter life is required because, relative to other types of filters, depth filters can retain a large mass of particles before becoming clogged.

Parameter

Connector	Luer or Quick Clamp Fittings
Animal-derived	All filters are made of synthetic materials and are not derived from animals
Integrity test	Pass the aerosol test
Operating pressure	Inlet pressure≤3bar
Operating temperature	≤37℃
Alkali resistance	45min At 25°C, the maximum resistance to 0.5N sodium hydroxide is 45min
pH	2-13
Sterilization method	Steam sterilization, ethylene oxide sterilization, gamma-ray sterilization

Types of Depth Filter

The depth filter produced by our company mainly include the following types:

Depth Filtration Capsule
Depth filtration capsule is a self-contained, disposable filter unit that traps and retains particulate matter throughout the thickness (or depth) of its media, rather than just on the surface.

Single-Use Depth Filter
Single-use depth filter is a disposable, non-woven filter used to separate solids from liquids by capturing particles throughout the entire thickness of the filter media, rather than just on the surface.

Advantages of Depth Filter

High particle holding capacity
As the particles are retained inside the filter medium, a depth filter can hold a larger quantity of solids.

Efficient for small particles
Depth filters are particularly suitable for the filtration of very fine particles.

Applications of Depth Filter

Pre-Filtration in Water Treatment Plants
Depth filters are crucial in removing large particles and sediments from raw water. They serve as the first line of defense, preventing clogging and damage to downstream ultrafiltration or reverse osmosis units.

Oil & Gas Downstream Processing
In oil refining, depth filters remove particulates from crude oil and process fluids, ensuring purity before chemical treatments or final product extraction. They help prevent equipment wear and improve product quality.

Pharmaceutical Manufacturing
In pharmaceutical production, purity is paramount. Depth filters are used during the sterilization process to remove bacteria, endotoxins, and particulates from liquids. They are integral in ensuring compliance with strict regulatory standards like GMP (Good Manufacturing Practice).

Food & Beverage Processing
Depth filters are employed to clarify liquids such as juices, wines, and dairy products. They remove suspended solids, yeast, and bacteria, ensuring product clarity and stability. Their ability to handle viscous fluids and large volumes makes them ideal for continuous processing lines.

Chemical Manufacturing & Processing
In chemical plants, depth filters serve to remove catalysts, pigments, and other particulates from process streams. They help maintain process integrity and prevent equipment fouling. These filters are selected based on chemical compatibility and flow requirements.

Membrane Filter vs Depth Filter: Key Differences

Comparison Dimension	Membrane Filter	Depth Filter
Filtration Type	Surface filtration	Depth filtration
Retention Mechanism	Absolute-rated micropores	Multi-layer gradient pores
Filtration Precision	High (microorganism control)	Nominal (large particle removal)
Dirt-Holding Capacity	Low	High
Service Life	Shorter	Longer
Integrity Testing	Yes	No
Cost	Higher	Lower
Best Applications	Final filtration, sterile applications	Pre-filtration, high particle loads

Deep Filter Installation Guide

Handling Precautions

Depth filter sheets should be carefully handled into the plate and frame filter during installation to maintain structural integrity
Avoid banging, bending, and rubbing the sheets
Discard sheets with visible damage prior to use

Direction Control

Rough Surface (Unfiltered Side): Faces the feed stream inlet
Smooth Surface (Filtrate Side): Contacts the polished filtrate plate

Critical Alignment

Ensure smooth filtrate side aligns with clean plate grooves
Verify directional arrows on sheet edge match flow indicators

Customizable Options

Pore Size	0.2 µm / 0.45 µm / 1 µm / 5 µm
Filtration Mode	Clarification / Pre-filtration / Sterile filtration
Flow Capacity	1 L/h – 100 L/h (depends on scale)
Dirt Holding Capacity	High / Medium / Custom grade
Housing Material	PP / PE / Stainless steel housing
Filter Depth	1 mm – 10 mm (multi-layer design)
Particle Retention	0.1 µm – 10 µm range

Packaging and Shipping

Packaging

Inner Packaging: Sterile protective bag or shrink wrap

Outer Packaging: Extra-thick cardboard carton

Shipping

For small quantity or sample will be shipped by DHL, FEDEX ,TNT ( shipping days 3-4 days).

For bigger quantity will be shipped by sea shipment to your pointed nearest seaport ( shipping days 1 month).

Our Factory

Our factory is located in the Hangzhou City, we have 5 production lines, which can produce 8000pcs cassettes and 5000pcs holders, and have about 100 workers in the factory.

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FAQ

Q: How do depth filters work?

A: Depth filters pass liquids through a tortuous maze of filter fibres that gradually become more compact. As the fluid passes further through this filter bed, smaller and smaller sizes of particulate contamination are removed by a filtration mechanism known as mechanical sieving. It’s like hitting a golf ball through a forest. Although the golf ball is small, the complex nature and depth of the branches it passes through lead to it being captured and retained.

Q: What are the different constructions of depth filters, and why are they necessary?

A: In cartridge filtration products, there are three types of depth filters:
Spun or meltblown construction is used in an application where the size range of contaminants is unknown or can vary. Through the filter matrix thickness of 25,000 microns (25 mm), retention is graded with larger particles retained first and smaller particles progressively removed.
Pleated depth construction can be tailored to effectively remove the size range of contaminants when it’s known, allowing the media to be far thinner (1,500 microns (1.5 mm). The media can then be pleated, allowing a greater surface area to maximise cartridge life.
A hybrid pleated depth filter was developed to retain contaminants that are not solid particles and could not fully be retained by a pleated depth filter. In specific applications, contaminants are gelatinous, extrudable, or colloidal. The thicker pleated media (3-5,000 microns (3-5 mm)) offers the retention required without loss of service life.

Q: Where are depth filters used?

A: Depth cartridge filter remove particulates such as particles, gels, organic solids, hazes, agglomerations, yeasts, and moulds. This ensures the visual clarity of liquids and prevents the damage, blockage, or wear and tear of process pipework and equipment. By removing large particulate matter from fluid streams, they act as prefilters and perform an important role. Protecting membrane cartridge filters or RO modules maximises their service life.

Q: Are depth filters reusable?

A: Depth filters are intended for continuous use over long periods and are changed when blocked. They can be used and stored before being used again if the manufacturer’s instructions are followed on the storage procedure. However, depth filters are difficult to clean by backflush due to the complicated nature of the depth filter structure. A small degree of regeneration can be achieved, but it is unlikely to be worth the effort required.

Q: Are depth filters different to membrane filters?

A: Depth filters and membrane filters are two distinct types of filtration media. Depth filters use the tortuous path through a filter bed, a complex maze of fibres 1,000 microns thick, to remove particulate. On the other hand, membranes have a more homogenous structure, and filtration typically occurs on or near the membrane’s surface, which is usually 100 microns thick.

We're well-known as one of the leading depth filter manufacturers and suppliers in China. If you're going to wholesale bulk high quality depth filter in stock, welcome to get free sample from our factory.

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