Advance Centrifugal Devices

Description
Guidling advance centrifugal devices provide fast ultrafiltration, with the capability for high concentration factors and easy concentrate recovery from dilute and complex sample matrices. The ultrafiltration of advance centrifugal devices will not accomplish a sharp separation of two molecules with similar molecular weights. The molecules to be separated should differ by at least one order of magnitude (10X) in size for effective separation. Fractionation using ultrafiltration is effective in applications, such as the preparation of protein-free filtrates, the separation of unbound or unincorporated label from DNA and protein samples, and the purification of PCR products from synthesis reactions.

Choosing the correct MWCO
Once sample volume is determined, the next step is to select the appropriate MWCO (for ultrafiltration) or pore size (for microfiltration). MWCOs are nominal ratings based on the ability to retain > 90% of a solute of a known molecular weight (in kilodaltons). Advance centrifugal devices provide retention characteristics of different MWCO membranes for some solutes. For proteins, it is recommended that an MWCO be selected that is three to six times smaller than the molecular weight of the solute being retained. If flow rate is a consideration, choose a membrane with an MWCO at the lower end of this range (3X); if the main concern is retention, choose a tighter membrane (6X).

It is important to recognize that retention of a molecule by an ultrafiltration membrane is determined by a variety of factors, among which its molecular weight serves only as a general indicator.

Therefore, choosing the appropriate MWCO for a specific application requires the consideration of a number of factors including molecular shape, electrical charge, sample concentration, sample composition, and operating conditions. Because different manufacturers use different molecules to define the MWCO of their membranes, it is important to perform pilot experiments to verify membrane performance in a particular application

Our Services
1.Quick response
All requests will be reply within 12 hours.
2.Shipping Method:
For small quantity or sample will be shipped by DHL, FEDEX ,TNT ( shipping days 3-4 days)
For bigger quantity will be shipped by sea shipment to your pointed nearest seaport ( shipping days 1 month)

FAQ：
Q: Do you deal with urgent orders?
A: Sure. Please contact ASAP for details by email, by Whatsapp or by Wehcat .

Q: I bought from you once. Can I have a special offer this time?
A: Contact for details. We do value our customers; we can and will offer you good price.

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