PES Hollow Fiber
The PES Hollow fiber represents a remarkable innovation in the realm of liquid filtration. At its core, it features countless microscopic hollow fibers intricately arranged within the filter medium. These hollow fibers act as highly selective barriers, allowing only specific components to pass through while retaining unwanted particles and contaminants.
Product Introduction
Description
The PES Hollow fiber represents a remarkable innovation in the realm of liquid filtration. At its core, it features countless microscopic hollow fibers intricately arranged within the filter medium. These hollow fibers act as highly selective barriers, allowing only specific components to pass through while retaining unwanted particles and contaminants. This results in the production of cleaner, safer liquids.
The operation of the PES hollow fiber is efficient. When a liquid mixture is introduced into the PES hollow fiber filter, it undergoes a transformative process. The microscopic pores on the surface of the PES hollow fibers act as gatekeepers, allowing smaller molecules and pure liquid to pass through, while trapping larger particles and impurities.
Product Specification
|
Parameters of PES hollow fiber with inner diameter of 1.0mm |
||||||||||
|
specs |
tube inner diameter（mm) |
Tube Outer diameter（mm) |
Valid length（cm) |
Inner diameter of fiber（mm) |
Processing capacity |
MWCO |
Fiber quantity |
Filter area |
Inlet/reflux |
Permeate |
|
xs |
13 |
16 |
30 |
1.0 |
<1L |
30kd 100kd 300kd 500kd 750kd 0.2um 0.45um |
10 |
94cm2 |
25TC |
Luer |
|
S |
13 |
16 |
30 |
1.0 |
<3L |
28 |
260cm² |
|||
|
M |
36 |
40 |
30 |
1.0 |
<15L |
160 |
0.15㎡ |
25TC/50TC |
25TC |
|
|
60 |
1.0 |
<30L |
160 |
0.3㎡ |
||||||
|
L |
108 |
114 |
60 |
1.0 |
<500L |
2400 |
4.5㎡ |
Not applicable |
Not applicable |
|
|
120 |
1.0 |
<1000L |
2400 |
9㎡ |
||||||
|
Parameters of PES hollow fiber with inner diameter of 0.5mm |
||||||||||
|
specs |
tube inner diameter（mm） |
tube outer diameter（mm) |
Valid length（cm) |
Inner diameter of fiber（mm) |
Processing capacity |
MWCO |
Fiber quantity |
Filter area |
Inlet/reflux |
Permeate |
|
XS |
13 |
16 |
30 |
0.5 |
<1L |
30kd 100kd 300kd 500kd 750kd 0.2um 0.45um |
20 |
94cm2 |
25TC |
25TC |
|
S |
13 |
16 |
30 |
0.5 |
<3L |
56 |
260cm2 |
|||
|
M |
36 |
40 |
30 |
0.5 |
<15L |
320 |
0.15㎡ |
25TC |
25TC |
|
|
60 |
0.5 |
<30L |
320 |
0.3㎡ |
||||||
|
L |
108 |
114 |
60 |
0.5 |
<500L |
4800 |
4.5㎡ |
Not applicable |
Not applicable |
|
|
120 |
0.5 |
<1000L |
4800 |
9㎡ |
||||||
|
[Steam sterilization resistance series] Parameters of PES hollow fiber with inner diameter of 1.0mm |
||||||||||
|
Specs |
tube inner diameter（mm) |
tube outer diameter（mm) |
Valid length（cm) |
Inner diameter of fiber（mm) |
Processing capacity |
MWCO |
Fiber quantity |
Filter area |
Inlet/reflux |
Permeate |
|
L |
108 |
114 |
60 |
1.0 |
<500L |
10kd 30kd 300kd 500kd |
2400 |
4.5㎡ |
Not applicable |
Not applicable |
|
120 |
1.0 |
<1000L |
2400 |
9㎡ |
||||||
|
[Steam sterilization resistance series] Parameters of PES hollow fiber with inner diameter of 0.5mm |
||||||||||
|
Specs |
tube inner diamete（mm) |
tube outer diameter（mm) |
Valid length（cm) |
Inner diameter of fiber（mm) |
Processing capacity |
MWCO |
Fiber quantity |
Filter area |
Inlet/reflux |
Permeate |
|
L |
108 |
114 |
60 |
0.5 |
<500L |
10kd 30kd 300kd 500kd |
4800 |
4.5㎡ |
Not applicable |
Not applicable |
|
120 |
0.5 |
<1000L |
4800 |
9㎡ |
||||||
FAQs
Q1. In the field of biopharmaceuticals, what drug manufacturing processes can use hollow fibers?
Hollow fiber can be used in many drug manufacturing processes in the field of biopharmaceuticals, such as cell culture, separation and purification, protein purification, and depth filtration. They are usually used as a means of separating impurities, reducing contamination, increasing yield and increasing purity.
Q2. Which steps can use hollow fiber in gene therapy, cell therapy companies?
In gene therapy and cell therapy companies, hollow fibers can be used in these process, such as cell culture, cell separation, washing, concentration, purification, etc. Specific applications include:
Cell culture: hollow fibers can be used as support materials for cell culture, providing greater cell density and surface area.
Cell separation: hollow fibers can be used for cell isolation and collection, increasing the purity and productivity of individual cells
Washing and concentration: hollow fibers can be used for washing, protein concentration and cell preparation.
Purification: hollow fibers can be used in the purification steps of biological agents such as proteins, viruses, and plasmids to improve product purity and productivity.
Q3:How to choose hollow fiber or flat cassettes in tangential flow filtration technology
Compared with hollow fibers, the microfiltration membrane of flat cassettes has greater limitations in the clarification and filtration of high-solid content and high-viscosity samples, and are easy to block the flow channel. The screen channel structure is suitable for the concentration of low viscosity and low concentration samples without solid particles, such as buffer exchange and concentration between chromatographic columns.
|
Application |
Hollow fiber |
Flat cassettes |
|
E. coli collection |
√ |
× |
|
yeast clarification |
√ |
× |
|
Clarification after E. coli mean |
√ |
√ |
|
Yeast fermentation broth clarification |
√ |
√ |
|
The ultrafiltration concentration of the recombinant proteins |
√ |
√ |
|
Perfusion culture |
√ |
× |
|
Ultrafiltration of viral vector mRNA |
√ (Subunits, LNP particles, multimeric proteins or particles) |
√ (More suitable for small particle size) |
|
Large intestine renaturing solution clarification |
√ (priority) |
√ |
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