Tangential Flow Refers To The Filtration Form in Which The Liquid Flow Direction Is Perpendicular To The Filtration Direction

Tangential flow refers to the filtration form in which the liquid flow direction is perpendicular to the filtration direction. The traditional dead end, also known as vertical filtration, is the most commonly used form of MF filtration, including filtration. The flow direction of the liquid is consistent with the direction of filtration. With the filtration process, the thickness of the cake layer or gel layer formed on the surface of the filter membrane is gradually increasing and the flow rate is gradually decreasing. When the filter medium is ultrafiltration membrane or microfiltration membrane with small pore size and the solid content in the feed liquid is very high, the dead end filtration method will be adopted, and the flow rate will be reduced rapidly. Therefore, the dead end filtration can only deal with small volume of feed liquid.

Tangential flow ultrafiltration system is mainly used in the concentration, purification, dialysis (desalting and dealcoholization, etc.) of biological products, replacement buffer, culture solution and buffer heat removal

Tangential flow microfiltration system is mainly used in downstream treatment in bioengineering field, such as replacing centrifuge to collect cells from fermentation broth and remove cell debris